In this tutorial, I will show you how to show Google Adsense Ads or any Ads to appear only on homepage.
Use below code for this:

<?php if(is_home() && $post==$posts[0] && !is_paged()) { ?>
     Google Adsense Code Here
<?php } ?>

Another method is:

<?php if (is_front_page()) : ?>
Google Adsense Code Here
<?php endif; ?>

In above code, just replace Google Adsense Code Here to your actual Adsense code. You can use any code that you want to appear only on homepage of WordPress.